新产品编号:1762857
Chemical Name: (?-N-[2-(7-Methoxynaphthalen-1-yl)propyl]butyramide
项目整合开发状态: Biological Testing
项目研究机构: CNRS (Originator)
合成路线:Alkylation of (7-methoxy-1-naphthyl)acetonitrile (I) with iodomethane in the presence of NaH gave the corresponding naphthylpropionitrile (II),which was reduced to amine (III) by catalytic hydrogenation over Raney-Ni.Finally,condensation of (III) with butyryl chloride in the presence of triethylamine provided the title butyramide.
📌 参考资料/链接：
参考文献标题:Synthesis of beta-substituted naphth-1-yl ethylamido derivatives as new melatoninergic agonists
文献作者:Math?Allainmat,M.; le Gall,M.; Jellimann,C.; Andrieux,J.; Langlois,M.
参考来源:Bioorg Med Chem 1999,7(12),2945