Salvicine
Chemical Name: 8-(3,4-Dihydroxy-4-methylpentyl)-3-isopropyl-7-methylnaphthalene-1,2-dione
项目整合开发状态: Preclinical
项目研究机构: Chinese Academy of Sciences (Originator)
合成路线:The epoxidation of naphthoquinone (I) with MCPBA in chloroform gives the epoxide (II),which is hydrolyzed with water and HClO4 to yield the target diol,along with other reaction products that are separated by column chromatography over silicagel.
📌 参考资料/链接：
参考文献标题:Synthesis and antitumour activity of novel diterpenequinone salvicine and the analogs
文献作者:Zhang,J.S.; Ding,J.; Tang,Q.M.; Li,M.; Zhao,M.; Lu,L.J.; Chen,L.J.; Yuan,S.T.
参考来源:Bioorg Med Chem Lett 1999,9(18),2731