新产品编号:1696413

Chemical Name: 1-[4-(4-Fluorophenyl)-4-oxobutyl]piperidine-4-carboxylic acid methyl ester
项目整合开发状态: Preclinical
项目研究机构: Central Drug Research Institute (Originator)
合成路线:The reaction of piperidine-4-carboxylic acid (I) with SOCl2 gives the acyl chloride (II),which is treated with methanol to yield the methyl ester (III).Finally,this compound is condensed with 4-chloro-1-(4-fluorophenyl)-1-butanone (IV) by means of K2CO3 in refluxing acetone.