新产品编号:1688503
Chemical Name: 1-(4'-Fluorobiphenyl-4-ylmethyl)-1H-imidazole
项目整合开发状态: Preclinical
项目研究机构: Universit鋞 des Saarlandes (Originator)
合成路线:This compound has been obtained by condensation of 1-(4-bromobenzyl)imidazole (I) with 4-fluorophenylboronic acid (II) by means of Pd(PPh3)4 and Na2CO3 in refluxing toluene/ethanol.
📌 参考资料/链接：
参考文献标题:Imidazole substituted biphenyls: A new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer
文献作者:Wachall,B.G.; Hector,M.; Zhuang,Y.; Hartmann,R.W.
参考来源:Bioorg Med Chem 1999,7(9),1913