新产品编号:1658445
Chemical Name: 2-(2',4'-Dichlorobiphenyl-4-yl)-6-fluoroquinoline-4-carboxylic acid
项目整合开发状态: Biological Testing
项目研究机构: Cubist (Originator)
合成路线:The title quinolinecarboxylic acid was synthesized by Pfitzinger condensation of 5-fluoroisatin (I) with 1-(2',4'-dichlorobiphenyl-4-yl)ethanone (II) in the presence of KOH in aqueous EtOH.
📌 参考资料/链接：
参考文献标题:Structure-activity relationship of biphenylquinoline analogs as inhbitors of S.aureus methionyl-TRNA synthetase
文献作者:Yu,X.Y.; et al.
参考来源:218th ACS Natl Meet (Aug 22 1999,New Orleans) 1999,Abst MEDI 296