新产品编号:1656863
Chemical Name: 2-(4-Bromophenyl)-6-chloro-8-methylquinoline-4-carboxylic acid
项目整合开发状态: Biological Testing
项目研究机构: Cubist (Originator)
合成路线:The title quinoline derivative was prepared by a Pfitzinger synthesis employing 5-chloro-7-methylisatin (I) and 4'-bromoacetophenone (II) in ethanolic KOH.
📌 参考资料/链接：
参考文献标题:Structure-activity relationship of quinoline analogs as inhibitors of C.albicans prolyl t-RNA synthetase
文献作者:Hill,J.M.; Kluge,A.F.; Silverman,J.; Yang,Y.; Yu,G.; Finn,J.; Keith,D.; Yu,X.Y.; Gallant,P.
参考来源:218th ACS Natl Meet (Aug 22 1999,New Orleans) 1999,Abst MEDI 289