BM2419-1

Chemical Name: 1,3,6,8,10,11-Hexahydroxynaphthacene-5,12-dione
项目整合开发状态: Biological Testing
项目研究机构: Kaken (Originator)
合成路线:Title compound was generated during the extraction of saintopin (I) from the mycelia of the fungal strain Paecilomyces sp.BM2419 upon irradiation with a halogen lamp the saintopin extracts dissolveld in 90% aqueous pyridine,and was finally purified by preparative HPLC.

合成路线:Title compound was generated during the extraction of saintopin (I) from the mycelia of the fungal strain Paecilomyces sp.BM2419 upon standing for several days the saintopin extracts dissolveld in DMSO,and was finally purified by C18 solid extraction,followed by preparative HPLC.
📌 参考资料/链接:
参考文献标题:Novel selective inhibitors for human topoisomerase I,BM2419-1 and -2 derived from saintopin
文献作者:Ishiyama,D.; Futamata,K.; Futamata,M.; Kasuya,O.; Kamo,S.; Yamashita,F.; Kanazawa,S.
参考来源:J Antibiot 1998,51(12),1069