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新产品编号:1394251

Chemical Name: N-[2-(3,4-Dimethoxyphenyl)ethyl]-4,5-dihydrooxazole-2-amine hydrochloride; N-(4,5-Dihydrooxazol-2-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]amine hydrochloride
项目整合开发状态: Preclinical
项目研究机构: China Pharmaceutical University (Originator)
合成路线:Acid-catalyzed condensation of ethanolamine (I) with urea (II) produced oxazolidinone (III).Subsequent reaction of (III) with triethyloxonium fluoborate yielded ethoxyoxazoline (IV).This was finally condensed with 2-(3,4-dimethoxyphenyl)- ethylamine to afford the title compound,which was isolated as the hydrochloride salt.
📌 参考资料/链接:
参考文献标题:Synthesis of imidazoline,oxazoline derivatives and antihypertensive activity
文献作者:Xu,J.Y.; et al.
参考来源:J Chin Pharm Univ 1998,29(5),336