新产品编号:1356283
Chemical Name: 4-[4-(4-Acetylphenyl)piperazin-1-yl]-7,9-diphenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidine; 4-[4-(7,9-Diphenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)piperazin-1-yl]acetophenone
项目整合开发状态: Biological Testing
项目研究机构: Universidad de Santiago de Compostela (Originator), Universidade da Coru馻 (Originator)
合成路线:Refluxing aminocarboxamide (I) with triethyl orthoformate afforded the pyridothienopyrimidine (II).Then,treatment of (II) with PCl5 and POCl3 yielded the corresponding chloro derivative (III).Finally,the title compound was obtained by substitution of the chloro group with N-(4-acetylphenyl)piperazine (IV) in refluxing ethanol.
📌 参考资料/链接:
参考文献标题:Synthesis and antiallergic activity of pyridothienopyrimidines
文献作者:Quintela,J.M.; Peinador,C.; Veiga,C.; Gonzalez,L.; Botana,L.M.; Alfonso,A.; Riguera,R.
参考来源:Bioorg Med Chem 1998,6(10),1911