新产品编号:1199665
Chemical Name:
项目整合开发状态: Biological Testing
项目研究机构: University of Bath (Originator)
合成路线:Pechmann condensation of resorcinol (I) with ethyl 2-methylacetylacetate (II) in concentrated sulfuric acid at room temperature provided coumarine (III).Further treatment with one equivalent of sodium hydride and an excess of sulfamoyl chloride yielded the target sulfamate.
📌 参考资料/链接：
参考文献标题:Steroidal and nonsteroidal sulfamates as potent inhibitors of steroid sulfatase
文献作者:Woo,L.W.C.; Howarth,N,M.; Purohit,A.; Hejaz,H.A.; Reed,M.J.; Potter,B.V.L.
参考来源:J Med Chem 1998,41(7),1068