AH-1058

Chemical Name: 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[3-(3-methoxy-2-nitrophenyl)-2(E)-propenyl]piperidine hydrochloride
项目整合开发状态: Preclinical
项目研究机构: Ajinomoto (Originator)
合成路线:Treatment of 3-methoxy-2-nitrocinnamyl alcohol (I) with SOCl2 provided the corresponding chloride (II),which was then condensed with dibenzocycloheptylidenepiperidine (III) in the presence of K2CO3 and NaI in hot methyl isobutyl ketone to yield the title compound.