新产品编号:2454191

Chemical Name: 4-[1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-ylmethyl]thiomorpholine
项目整合开发状态: Biological Testing
项目研究机构: Universit?degli Studi "La Sapienza" (Originator), Universit?degli Studi di Cagliari (Originator), Universit?degli Studi di Siena (Originator)
合成路线:Condensation between 1-phenyl-1,4-pentanedione (I) and 4-fluoroaniline (II) under Paal-Knorr reaction conditions provides the pyrrole derivative (III).This is then subjected to Mannich reaction with thiomorpholine (IV) and formaldehyde to furnish the target thiomorpholimomethyl pyrrole.