A-00000762, A-762
Chemical Name: 2-(4-Nitrophenyl)benzo-1,4-quinone
项目整合开发状态: Biological Testing
项目研究机构: Arrow Therapeutics (Originator)
合成路线:Diazotization of 4-nitroaniline (I) with NaNO2 in cold concentrated HCl produces diazonium salt (II),which is subsequently coupled to 1,4-benzoquinone (III) in the presence of NaHCO3 to furnish the target 2-aryl benzoquinone.
📌 参考资料/链接:
参考文献标题:The identification of nanomolar 1,4-benzoquinone inhibitors of shikimate kinase
文献作者:Reynolds,K.; et al.
参考来源:42nd Intersci Conf Antimicrob Agents Chemother (Sept 27 2002,San Diego) 2002,Abst F-745