新产品编号:2346615

Chemical Name: 1-(4-Fluorophenyl)-1-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol
项目整合开发状态: Biological Testing
项目研究机构: Harvard Medical School (Originator), Massachusetts General Hospital (Originator), Yale University (Originator)
合成路线:Alkylation of 4-(p-fluorobenzoyl)piperidine (I) with p-fluorophenethyl bromide (II) in hot methyl isobutyl ketone provides the disubstituted piperidine (III).Subsequent keto group reduction in (III) by means of NaBH4 furnishes the title carbinol compound.