新产品编号:2232711

Chemical Name: 1'-Benzyl-17-(cyclopropylmethyl)-6,7-didehydro-4,5alpha-epoxy-3,14beta-dihydroxy-4'-phenylpyrrolo[2',3':6,7]morphinan
项目整合开发状态: Preclinical
项目研究机构: University of Bath (Originator), University of Bristol (Originator), University of Michigan (Originator), University of Virginia (Originator)
合成路线:Condensation of naltrexone (I) with benzylamine produces the intermediate imine (II) which is subsequently cyclized with trans-beta-nitrostyrene (III) to produce the required pyrrolomorphinan.