新产品编号:2117225

Chemical Name: 3-[1-[3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxyphenylsulfonyl]piperidin-4-yl]propionic acid
项目整合开发状态: Biological Testing
项目研究机构: SK Chemicals (Originator)
合成路线:Chlorosulfonylation of the benzamidopyrazole (I) to give (II) was performed with neat chlorosulfonic acid at 0 C.Coupling of sulfonyl chloride (II) with the piperidinopropanoate (III) provided sulfonamide (IV).Finally,cyclization of (IV) with concomitant ester hydrolysis under basic conditions furnished the target pyrazolopyrimidine.