OP-1030

Chemical Name: 4-[4-(2-Methoxyphenyl)piperazin-1-yl]-N,N-dimethyl-2,2-diphenylbutyramide hydrochloride
项目整合开发状态: Preclinical
项目研究机构: SSP (Originator)
合成路线:The target disubstituted piperazine was generated by the ring opening of dimethyl (tetrahydro-3,3-diphenyl-2-furylidene)ammonium bromide (I),equivalent to the open-chain bromobutyramide,with N-(2-methoxyphenyl)piperazine (II) in hot DMF.Subsequent treatment with HCl in CHCl3-Et2O provided the corresponding hydrochloride salt.