新产品编号:2065019

Chemical Name: 6-Chloro-N-(4-fluorophenyl)pyridine-3-carboxamide 1-oxide
项目整合开发状态: Preclinical
项目研究机构: Celltech (Originator)
合成路线:6-Chloronicotinic acid (I) was converted to the corresponding N-oxide (II) using trifluoroperacetic acid.Acid (II) was subsequently condensed with 4-fluoroaniline (III) using EEDQ as the coupling reagent to provide the target amide.