新产品编号:2063437
Chemical Name: 2,6-Diisopropyl-4-(4-morpholinylmethyl)phenol hydrochloride
项目整合开发状态: Preclinical
项目研究机构: Organon (Originator)
合成路线:The title compound was obtained by Mannich reaction between 2,6-diisopropylphenol (I),morpholine (II) and formaldehyde,followed by conversion to the corresponding hydrochloride salt.
📌 参考资料/链接：
参考文献标题:Novel water-soluble propofol analogs with intravenous anaesthetic activities
文献作者:Buchanan,K.; et al.
参考来源:222nd ACS Natl Meet (Aug 26 2001,Chicago) 2001,Abst MEDI 226
📄 详细内容
合成路线:The title compound was obtained by Mannich reaction between 2,6-diisopropylphenol (I),morpholine (II) and formaldehyde,followed by conversion to the corresponding hydrochloride salt.
参考文献标题:Water-soluble propofol analogues with intravenous anaesthetic activity
文献作者:Cooke,A.; Anderson,A.; Buchanan,K.; Byford,A.; Gemmell,D.; Hamilton,N.; McPhail,P.; Miller,S.A.; Sundaram,H.; Vijn,P.
参考来源:Bioorg Med Chem Lett 2001,11(7),927