新产品编号:2049199

Chemical Name: N,N'-Bis[3-(biphenyl-3-ylmethylamino)propyl]heptane-1,7-diamine
项目整合开发状态: Preclinical
项目研究机构: Albert Einstein College of Medicine (Originator), Johns Hopkins University (Originator), Pace University (Originator), Wayne State University (Originator)
合成路线:The known tetrasulfonamide (I) was alkylated with m-phenylbenzyl bromide (II) in the presence of NaH to afford the dialkylated derivative (III).The mesitylenesulfonyl protecting groups of (III) were then removed by treatment with HBr in HOAc to furnish the title tetramine.