新产品编号:2012813
Chemical Name: 2-Acetyl-N-benzyl-1-(2-thiazolyl)hydrazinecarboxamide
项目整合开发状态: Preclinical
项目研究机构: National Institutes of Health (Originator), University of Houston (Originator), University of North Carolina (Originator)
合成路线:Acetylation of 2-thiazolylhydrazine (I) with Ac2O in pyridine gave hydrazide (II).This was then converted to the title semicarbazide by carbamoylation with benzyl isocyanate (III) in the presence of DMAP.
📌 参考资料/链接：
参考文献标题:Synthesis and structural studies of aza analogues of functionalized amino acids: New anticonvulsant agents
文献作者:Andurkar,S.V.; Beguin,C.; Stables,J.P.; Kohn,H.
参考来源:J Med Chem 2001,44(9),1475