DA-3003-2

Chemical Name: 7-Chloro-6-[2-(4-morpholinyl)ethylamino]-5,8-dihydroquinoline-5,8-dione
项目整合开发状态: Biological Testing
项目研究机构: National Cancer Institute (Originator), University of Pittsburgh (Originator)
合成路线:The condensation of 6,7-dichloroquinoline-5,8-dione (I) with 4-(2-aminoethyl)morpholine (II) provided a 2:1 mixture of the title 7-amino quinoline and its 6-amino regioisomer (III),which were separated by column chromatography.

合成路线:The condensation of 6,7-dichloroquinoline-5,8-dione (I) with 4-(2-aminoethyl)morpholine (II) provided a 1:2 mixture of the title 6-amino quinoline and its 7-amino regioisomer (III),which were separated by column chromatography.