FR-86521

Chemical Name: (6R,7R)-7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2(Z)-(ethoxyimino)acetamido]-3-[3-amino-2-(2-hydroxyethyl)pyrazolium-1-ylmethyl]-3-cephem-4-carboxylic acid chloride
项目整合开发状态: Preclinical
项目研究机构: Fujisawa (Originator)
合成路线:Treatment of carboxylic acid (I) with PCl5 afforded the corresponding acid chloride (II).This was condensed with the 7beta-aminocephalosporin derivative (III),and the resulting amide was finally treated with HCl to provide the title compound.