新产品编号:2000157
Chemical Name: N,N'-Bis[3-(dimethylamino)propyl]dibenzo[b,j]-1,7-phenanthroline-2,10-dimethanamine
项目整合开发状态: Biological Testing
项目研究机构: CNRS (Originator)
合成路线:The title compound was prepared starting from dibenzo[b,j](1,7)phenanthroline-2,10-dicarboxaldehyde (I).Condensation of dialdehyde (I) with 3-(dimethylamino)propylamine (II) produced the intermediate diimine (III),which was then reduced to the corresponding amine by using NaBH4 in MeOH.
📌 参考资料/链接：
参考文献标题:Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay
文献作者:Mergny,J.-L.; Lacroix,L.; Teulade-Frchou,M.-P.; Hounsou,C.; Guittat,L.; Hoarau,M.; Arimondo,P.B.; Vigneron,J.P.; Lehn,J.M.; Riou,J.F.; Garestier,T.; Helene,C.
参考来源:Proc Natl Acad Sci USA 2001,98(6),3062