DTPA-M2
Chemical Name: 2-[N,N-Bis[2-[N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-ylcarbamoylmethyl]-N-(carboxymethyl)amino]ethyl]amino]acetic acid
项目整合开发状态: Preclinical
项目研究机构: Universit?degli Studi di Firenze (Originator)
合成路线:The title bis-amide was prepared by condensation of the dianhydride (I) with 5-amino-1,3,4-thiadiazole-2-sulfonamide (II).
📌 参考资料/链接：
参考文献标题:Carbonic anhydrase inhibitors: Synthesis of sulfonamides incorporating DTPA tails and of their zinc complexes with powerful topical antiglaucoma properties
文献作者:Scozzafava,A.; Menabuoni,L.; Muncione,F.; Mincione,G.; Supuran,C.T.
参考来源:Bioorg Med Chem Lett 2001,11(4),575