新产品编号:1974845

Chemical Name: Acetic acid 1-[2-(1H-imidazol-4-yl)-1(R)-methylethylcarbamoyloxy]ethyl ester
项目整合开发状态: Preclinical
项目研究机构: Freie Universit鋞 Berlin (Originator), INSERM (Originator)
合成路线:Treatment of p-nitrophenol (I) with 1-chloroethyl chloroformate (II) in the presence of pyridine afforded carbonate (III).Subsequent displacement of the chlorine atom of (III) with mercuric acetate in HOAc provided the acetoxy derivative (IV).This was then condensed with (R)-alpha-methylhistamine (V) in HMPT to furnish the title compound.