AWD-34-022
Chemical Name: 6-(2-Chlorobenzyl)-3,6-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
项目整合开发状态: Preclinical
项目研究机构: Asta Medica (Originator)
合成路线:Benzyl pyrazole derivative (III) was prepared by alkylation of 3-aminopyrazole-4-carboxamide (I) with 2-chlorobenzyl chloride (II) under phase-transfer conditions.Diazotization of (III) with NaNO2/HCl then gave the title pyrazolotriazinone.
📌 参考资料/链接:
参考文献标题:Pyrazolo[3,4-d][1,2,3]triazines with anticonvulsive action and methods for producing the same
文献作者:Lankau,H.-J.; Arnold,T.; Rostock,A.; Unverferth,K.; Kronbach,T.; Bartsch,R.(Arzneimittelwerk Dresden GmbH)
参考来源:DE 19924872; WO 0073309