K-12

Chemical Name: 8-(Difluoromethoxy)-1-ethyl-6-fluoro-7-[4-(2-methoxyphenyl)piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
项目整合开发状态: Biological Testing
项目研究机构: Daiichi Pharmaceutical (Originator), Ube (Originator)
合成路线:By the usual method of synthesis of fluoroquinolones: By condensation of 8-(difluoromethoxy)-6,7-difluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (I) with 1-(2-pyrimidinyl)piperazine (II) in pyridine.

合成路线:By the usual method of synthesis of fluoroquinolones: By condensation of 8-(difluoromethoxy)-1-ethyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (I) with 1-(2-methoxyphenyl)piperazine (II) in pyridine.