新产品编号:1903655
Chemical Name: 2-Methylfuro[2,3-g]isoquinoline-4,7,9(6H)-trione
项目整合开发状态: Preclinical
项目研究机构: Universit?Claude Bernard Lyon 1 (Originator)
合成路线:The title furoisoquinoline was synthesized by regioselective [4+2] cycloaddition between 5-bromo-2-methylbenzo[b]furan-4,7-dione (I) and 3-(tert-butyldimethylsilyloxy)-1-isopropoxy-2-aza-buta-1,3-diene (II),with simultaneous desilylation under the reaction conditions.
📌 参考资料/链接：
参考文献标题:Quinonic derivatives active against a virulent strain of Toxoplasma gondii.Synthesis of 2-methylfuro[2,3-g]- and [3,2-g]isoquinolinetriones
文献作者:Nebois,P.; Sarciron,M.E.; Bibal,B.; Bouammali,B.; Cherkaoui,O.; Pautet,F.; Petavy,A.F.; Walchshofer,N.; Fillion,H.
参考来源:Bioorg Med Chem Lett 2000,10(9),871