NE-10790
2-羟基-2-膦酰基-3-(吡啶-3-基)丙酸Chemical Name: 2-Hydroxy-2-phosphono-3-(3-pyridyl)propionic acid
CAS No. 152831-36-2
项目整合开发状态: Biological Testing
项目研究机构: Procter & Gamble (Originator)
合成路线:Treatment of ethyl 3-(3-pyridyl)-2-oxopropionate (I) with dimethyl phosphite (II) provides derivative (III),which is finally converted into the desired compound by hydrolysis with HCl.
📌 参考资料/链接：
参考文献标题:Phosphonocarboxylate cpds.for treating abnormal calcium and phosphate metabolism
文献作者:Bayless,A.V.; Dansereau,S.M.; Ebetino,F.H.(The Procter & Gamble Co.)
参考来源:EP 0788362; EP 0849272; US 5391743; US 5824661; WO 9324131