SCRC-2941-18
2-氨基-4-(4-氯苯基)-5-甲基噻唑Chemical Name: 4-(4-Chlorophenyl)-5-methylthiazol-2-amine
CAS No. 82632-77-7
项目整合开发状态: Preclinical
项目研究机构: Sagami (Originator)
合成路线:Bromination of 4'-chloropropiophenone (I) afforded bromoketone (II).This was cyclized with thiourea (III) to produce the target 4-arylthiazole.
📌 参考资料/链接：
参考文献标题:4-Phenylthiazole derivatives inhibit IL-6 secretion in osteoblastic cells and suppress bone weight loss in ovariectomized mice
文献作者:Yamaguchi,K.; Yada,M.; Tsuji,T.; Hatanaka,Y.; Goda,K.; Kobori,T.
参考来源:Bioorg Med Chem Lett 1999,9(7),957