Bornaprolol hydrochloride, FM-24
2-丙醇,1-(2-双环[2.2.1]庚-2-yl苯氧基)-3-[(1-甲基乙基)氨基]-,盐酸盐(1:1) 波那洛尔 Chemical Name: (?-1-(2-exo-Byciclo[2.2.1]hept-2-ylphenoxy)-3-[(1-methylethylamino]-2-propanol hydrochloride; (?-1-(Isopropylamino)-3-(o-2-exo-norbornylphenoxy)-2-propanol
CAS No. 69319-47-7, 66451-06-7 (free base)
项目整合开发状态: Biological Testing
项目研究机构: Pharmuka (Originator)
合成路线:The condensation of sodium 2-(2-exo-norbornyl)phenoxide [from 2-bicyclo[2.2.1]hept-2-ylphenol (I) and sodium] with epichlorohydrin (II) gives (III),which is then treated with isopropylamine (IV) and finally with isopropanolic HCl.
📌 参考资料/链接：
参考文献标题:Bornaprolol hydrochloride
文献作者:Michaud,R.
参考来源:Drugs Fut 1982,7(2),91
📄 详细内容
合成路线:The condensation of sodium 2-(2-exo-norbornyl)phenoxide [from 2-bicyclo[2.2.1]hept-2-ylphenol (I) and sodium] with epichlorohydrin (II) gives (III),which is then treated with isopropylamine (IV) and finally with isopropanolic HCl.
参考文献标题:
文献作者:
参考来源:FR 75/09997; FR 76/24360
产品链接: CAS No. 69319-47-7›› 产品链接: CAS No.66451-06-7››