KME-4
2(3H)-呋酮,3-[[3,5-双(1,1-二甲基乙基)-4-羟基苯]甲基]二氢-Chemical Name: alpha-(3,5-Di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolactone
CAS No. 83677-24-1
项目整合开发状态: Phase II
项目研究机构: Kaneka (Originator)
合成路线:By a Wittig condensation between 3,5-di-tert-butyl-4-hydroxybenzaldehyde (I) and a triphenylphosphorenylidene butyrolactone (II) in hot DMSO.
📌 参考资料/链接：
参考文献标题:3,5-di-Tert-butylstyrene derivatives,salts thereof and pharmaceutical compositions containing the same as an active ingredient
文献作者:Katsumi,I.; et al.(Kaneka Corp.)
参考来源:CA 1187505; EP 0057882; US 4431656
📄 详细内容
合成路线:By a Wittig condensation between 3,5-di-tert-butyl-4-hydroxybenzaldehyde (I) and a triphenylphosphorenylidene butyrolactone (II) in hot DMSO.
参考文献标题:Anti-inflammatory,analgesic and antipyretic pharmaceutical composition
文献作者:Katsumi,I.; et al.(Kaneka Corp.)
参考来源:CA 1167767; EP 0057881; US 4440784
合成路线:By a Wittig condensation between 3,5-di-tert-butyl-4-hydroxybenzaldehyde (I) and a triphenylphosphorenylidene butyrolactone (II) in hot DMSO.
参考文献标题:KME-4
文献作者:Castar,J.; Prous,J.
参考来源:Drugs Fut 1986,11(8),655
产品链接: CAS No. 83677-24-1››