新产品编号:967111
2-(3,4-二氢异喹啉-2(1H)-基)吡啶-4-胺 2-(1,2,3,4-四氢异喹啉-2-基)吡啶-4-盐酸胺 Chemical Name: 2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)pyridin-4-amine
CAS No. 524718-15-8, 524717-65-5 (monohydrochloride)
项目整合开发状态: Preclinical
项目研究机构: Roche (Originator)
合成路线:The title compound is prepared by condensation of 4-amino-2-bromopyridine (I) with an excess of tetrahydroisoquinoline (II) at 130 C
📌 参考资料/链接：
参考文献标题:2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists
文献作者:Btelman,B.; Alanine,A.; Bourson,A.; Gill,R.; Heitz,M.-P.; Mutel,V.; Pinard,E.; Trube,G.; Wyler,R.
参考来源:Bioorg Med Chem Lett 2003,13(5),829