YM-31636

2-(1H-咪唑-4-基甲基)-8H-茚并[1,2-d]噻唑单富马酸酯Chemical Name: 2-(1H-Imidazol-4-ylmethyl)-8H-indeno[1,2-d]thiazole monofumarate
CAS No. 159081-22-8
项目整合开发状态: Preclinical
项目研究机构: Yamanouchi (Originator)
合成路线:The title compound is prepared by condensation between 2-bromo-1-indanone (I) and 2-(4-imidazolyl)thioacetamide hydrochloride (II) in refluxing isopropanol,followed by treatment with fumaric acid in MeOH.