Bumecaine hydrochloride
1-丁基-N-(2,4,6-三甲基苯基)吡咯烷-2-甲酰胺盐酸盐 布美卡因 Chemical Name: 1-Butyl-N-(2,4,6-trimethylphenyl)-DL-prolinamide hydrochloride
CAS No. 19089-24-8, 30103-44-7 (free base)
项目整合开发状态: Not Determined
项目研究机构:
合成路线:By the reaction of alpha-bromo-delta-chlorovaleric acid chloride (I) with 2,4,6-trimethylaniline (II) and cyclization of the obtained amide (III) with n-butylamine (IV).
📌 参考资料/链接：
参考文献标题:Azociklolaktany.IX.Sintez i aniesteziruyushchaya aktivnost pirromekaina
文献作者:Fedina,I.V.; et al.
参考来源:Khim Farm Zh 1971,5(1),7-9
📄 详细内容
合成路线:By the reaction of alpha-bromo-delta-chlorovaleric acid chloride (I) with 2,4,6-trimethylaniline (II) and cyclization of the obtained amide (III) with n-butylamine (IV).
参考文献标题:Bumecaine Hydrochloride
文献作者:Kolwas,J.
参考来源:Drugs Fut 1979,4(3),170
产品链接: CAS No. 19089-24-8›› 产品链接: CAS No.30103-44-7››