Sitamaquine hydrochloride, Q45, WR-6026

1,6-己二胺,N1,N1-二乙基-N6-(6-甲氧基-4-甲基-8-喹啉)-,盐酸盐(1:2) 西罗莫斯 Chemical Name: 8-[6-(Diethylamino)hexylamino]-6-methoxy-4-methylquinoline dihydrochloride; 8-[6-(Diethylamino)hexylamino]-6-methoxyepidine dihydrochloride
CAS No. 5330-29-0, 57695-04-2 (free base)
项目整合开发状态: Phase III
项目研究机构: Walter Reed Army Institute (Originator), GlaxoSmithKline (Licensee)
合成路线:The title compound was prepared by heating 8-amino-6-methoxylepidine (I) with 6-(diethylamino)hexyl bromide (II) in the presence of Et3N,and was then converted to the corresponding dihydrochloride salt.