LL-11204, DL-204-IT
Chemical Name: 2-(3-Ethoxyphenyl)-5,6-dihydro-s-triazolo[5,1-a]isoquinoline; 2-(3-Ethoxyphenyl)-5,6-dihydro[1,2,4]triazolo[5,1-a]isoquinoline
CAS No. 55308-64-0
项目整合开发状态: Biological Testing
项目研究机构: Lepetit (Originator)
合成路线:By cyclization of 2-amino-3,4-dihydro-1(2H)-isoquinolinone (I) with m-ethoxybenzimidic acid ethyl ester (II) at 125 C.
合成路线:The cyclization of 2-amino-3,4-dihydro-1(2H)-isoquinolinone (I) with ethyl 4-chlorobenzimidate (II) by heating at 125 C under vacuum gives 2-(4-chloro-phenyl)-5,6-dihydro-s-triazolo[5,1-a]isoquinoline (III),which is dehydrogenated by means of N-bromoacetamide in refluxing CCl4.
📌 参考资料/链接：
参考文献标题:2-Substd.phenyl-5-triazols[5,1-a]isoquinoline cpds
文献作者:Consonni,P.; Lerner,L.; Omodei-Sal? A.(Lepetit SpA)
参考来源:US 4075341
📄 详细内容
合成路线:By cyclization of 2-amino-3,4-dihydro-1(2H)-isoquinolinone (I) with m-ethoxybenzimidic acid ethyl ester (II) at 125 C.
参考文献标题:Antifertility methods employing triazoloisoquinoline derivs.
文献作者:Lerner,L.; Omodei-Sale,A.; Consonni,P.(Lepetit SpA)
参考来源:DE 2424572
合成路线:By cyclization of 2-amino-3,4-dihydro-1(2H)-isoquinolinone (I) with m-ethoxybenzimidic acid ethyl ester (II) at 125 C.
参考文献标题:DL-204-IT
文献作者:Blancafort,P.; Serradell,M.N.; Castar,J.; Hillier,K.
参考来源:Drugs Fut 1981,6(1),23
产品链接: CAS No. 55308-64-0››