DPI-201106
Chemical Name: 4-[3-[4-(Diphenylmethyl)piperazin-1-yl]-2-hydroxypropoxy]-1H-indole-2-carbonitrile
CAS No. 78573-03-2, 78573-15-6 (methanesulfonate), 78573-14-5 (propanedioate)
项目整合开发状态: Phase II
项目研究机构: Novartis (Originator)
合成路线:By condesation of 4-(2,3-epoxypropoxy)-1H-indole-2-carbonitrile (I) with 1-(diphenylmethyl)piperazine (II).
📌 参考资料/链接：
参考文献标题:Use of 1,3-oxathiolane nucleoside analogues in the treatment of hepatitis B
文献作者:Belleau,B.; Nguyen-Ba,N.(BioChem Pharma Inc.)
参考来源:EP 0494119; JP 1994507150; US 5532246; WO 9211852
📄 详细内容
合成路线:By condesation of 4-(2,3-epoxypropoxy)-1H-indole-2-carbonitrile (I) with 1-(diphenylmethyl)piperazine (II).
参考文献标题:DPI-201106
文献作者:Koch,H.
参考来源:Drugs Fut 1985,10(12),979