新产品编号:666531
Chemical Name: 2(R),4-Dihydroxy-3,3-dimethyl-N-[2-(N-nonylcarbamoyl)ethyl]butyramide
CAS No. 25303-16-6 (undefined stereoch.)
项目整合开发状态: Biological Testing
项目研究机构: GlaxoSmithKline (Originator)
合成路线:3-Phthalimidopropionyl chloride (I) is condensed with n-nonylamine to produce the corresponding amide (II).Subsequent hydrazinolysis of phthalimide (II) furnishes the aminopropanamide (III),which is condensed with D-pantonolactone (IV) to yield the desired compound.
📌 参考资料/链接:
参考文献标题:N1-(Substituted) pantothenamides,antimetabolites of pantothenic acid
文献作者:Clifton,G.; Bryant,S.R.; Skinner,C.G.
参考来源:Arch Biochem Biophys 1970,137(2),523