M-HA
Chemical Name: 4-[4-[1-(Hydroxyamino)ethyl]phenyl]morpholine
CAS No. 475598-45-9
项目整合开发状态: Preclinical
项目研究机构: Mukogawa Women's University (Originator), Yokohama City University (Originator)
合成路线:4'-Morpholinoacetophenone (I) is condensed with hydroxylamine to produce the corresponding oxime (II).Subsequent reduction of oxime (II) using NaBH3CN gives rise to the title hydroxylamine compound (1,2).
📌 参考资料/链接：
参考文献标题:Anti-inflammatory and anti-allergic activities of hydroxylamine and related compounds
文献作者:Kataoka,H.; Horiyama,S.; Yamaki,M.; Oku,H.; Ishiguro,K.; Katagi,T.; Takayama,M.; Semma,M.; Ito,Y.
参考来源:Biol Pharm Bull 2002,25(11),1436
📄 详细内容
合成路线:4'-Morpholinoacetophenone (I) is condensed with hydroxylamine to produce the corresponding oxime (II).Subsequent reduction of oxime (II) using NaBH3CN gives rise to the title hydroxylamine compound (1,2).
参考文献标题:Solvents inducing oxidation of hydroxylamines
文献作者:Horiyama,S.; Suwa,K.; Yamaki,M.; Kataoka,H.; Katagi,T.; Takayama,M.; Takeuchi,T.
参考来源:Chem Pharm Bull 2002,50(7),996