LY-329332

Chemical Name: (3S,6R,7R,22R,23S,26S,36R,38aR)-22-(3-Amino-2,3,6-trideoxy-3-C-methyl-alpha-L-mannopyranosyloxy)-3-(carbamoylmethyl)-10,19-dichloro-44-[2-O-[3-(4'-fluorobiphenyl-4-ylmethylamino)-2,3,6-trideoxy-3-C-methyl-alpha-L-mannopyranosyl]-beta-D-glucopyranosyloxy]-7,28,30,32-tetrahydroxy-6-(N2-methyl-D-leucylamido)-2,5,24,38,39-pentaoxo-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-1H,22H-8,11:18,21-dietheno-23,26-(iminomethano)-13,16:31,35-dimetheno[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid
CAS No. 171099-39-1
项目整合开发状态: Preclinical
项目研究机构: Lilly (Originator)
合成路线:The target compound has been obtained by reductocondensation of glycopeptide (I) with 4'-fluorobiphenyl-4-carbaldehyde (II) by means of sodium cyanoborohydride in DMF/methanol.