新产品编号:818403

Chemical Name: 2-[2-(5-Bromo-2-methoxybenzylsulfanyl)-3-chlorophenyl]-1,4,5,6-tetrahydropyrimidine
CAS No. 325823-79-8
项目整合开发状态: Biological Testing
项目研究机构: Millennium (Originator)
合成路线:Condensation of 3-chloro-thiosalicylic acid (I) with 1,3-propanediamine (II) in boiling ortho-dichlorobenzene leads to the cyclic amidine (III).Subsequent alkylation of the thiol group of (III) with 5-bromo-2-methoxybenzyl chloride (IV) furnishes the target thioether
📌 参考资料/链接:
参考文献标题:Melanocortin-4 receptor binding cpds.and methods of use thereof
文献作者:Maguire,M.P.; Dai,M.; Vos,T.J.(Millennium Pharmaceuticals,Inc.)
参考来源:WO 0110842