SNJ-1558

Chemical Name: N1-[1(S)-[2-(Dimethylamino)acetylhydrazonomethyl]-3-methylbutyl]-N2-(4-fluorophenylsulfonyl)-L-valinamide
CAS No. 438003-89-5
项目整合开发状态: Preclinical
项目研究机构: Senju (Originator)
合成路线:Swern oxidation of the sulfonyl dipeptide alcohol (I) in the presence of sulfur trioxide-pyridine complex and DMSO affords aldehyde (II).This is then condensed with (dimethylamino)acetohydrazide (III) to produce the target N-acyl hydrazone