Tel-01
Chemical Name: 2,9-Bis[3-(4-morpholinyl)propyl]anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetrone
CAS No. 154355-15-4
项目整合开发状态: Biological Testing
项目研究机构: University of Texas System (Originator)
合成路线:The title bis-imide was synthesized by condensation of 3,4,9,10-perylenetetracarboxylic acid dianhydride (I) with N-(3-aminopropyl)morpholine (II) in hot n-butanol.
📌 参考资料/链接：
参考文献标题:Inhibition of human telomerase by a G-quadruplex-interaction cpd.
文献作者:Salazar,M.; Kerwin,S.M.; Hurley,L.H.; Fedoroff,O.Y.(University of Texas System)
参考来源:US 6156763; WO 9940087
📄 详细内容
合成路线:The title bis-imide was synthesized by condensation of 3,4,9,10-perylenetetracarboxylic acid dianhydride (I) with N-(3-aminopropyl)morpholine (II) in hot n-butanol.
参考文献标题:G-quadruplex DNA binding selectivity of perylenetetracarboxylic acid diimides is PH dependent and mediated by ligand aggregation
文献作者:Kerwin,S.M.; et al.
参考来源:222nd ACS Natl Meet (Aug 26 2001,Chicago) 2001,Abst MEDI 142