新产品编号:975021
Chemical Name: 1-Hydroxyheptylidene-1,1-diphosphonic acid
CAS No. 56375-74-7, 115330-54-6 (disodium salt)
项目整合开发状态: Biological Testing
项目研究机构: Universidad de Buenos Aires (Originator), University of Illinois (Originator)
合成路线:The reaction of heptanoic acid (I) with H3PO3,PCl3 and benzenesulfonic acid at 65 C,followed by a treatment in refluxing water gives the target diphosphonic acid.
📌 参考资料/链接：
参考文献标题:Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi
文献作者:Szajnman,S.H.; Bailey,B.N.; Docampo,R.; Rodriguez,J.B.
参考来源:Bioorg Med Chem Lett 2001,11(6),789