PR-9, ME-10092
Chemical Name: N1-(2-Chloro-3,4-dimethoxybenzylideneamino)guanidine acetate
CAS No. 332395-39-8, 284042-43-9 (free base)
项目整合开发状态: Preclinical
项目研究机构: Melacure Therapeutics (Originator)
合成路线:The title compound is prepared by condensation of 2-chloro-3,4-dimethoxybenzaldehyde (I) with aminoguanidine bicarbonate (II) in the presence of HOAc in refluxing MeOH.
📌 参考资料/链接：
参考文献标题:Guanidine derivs.and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase
文献作者:Skottner,A.; Lundstedt,T.; Seifert,E.; Veveris,M.; Piskunova,I.; Rozhkov,E.; Wikberg,J.; Pett,C.P.; Kalvins,I.; Andrianov,V.; Semenikhina,V.; Dambrova,M.(Melacure Therapeutics)
参考来源:WO 0125192