新产品编号:688679
Chemical Name: N2,N7,4-Trimethyl[1,8]naphthyridine-2,7-diamine
CAS No. 257864-51-0
项目整合开发状态: Biological Testing
项目研究机构: Friedrich-Schiller-Universit鋞 Jena (Originator), Hans Kn鰈l Institute Natural Prod. Res. (Originator)
合成路线:Hydroxynaphthyridinone (II),prepared from the amino derivative (I),was chlorinated to give dichloronaphthyridine (III).Subsequent copper-catalyzed substitution of both chloro groups by methylamine yielded the title compound.
📌 参考资料/链接：
参考文献标题:In vitro efficacy of 2,7-dialkylamino-[1,8]-naphtyridines against influenza viruses A and B
文献作者:Schmidtke,M.; et al.
参考来源:Antivir Res 2000,46(1),Abst 84
📄 详细内容
合成路线:Hydroxynaphthyridinone (II),prepared from the amino derivative (I),was chlorinated to give dichloronaphthyridine (III).Subsequent copper-catalyzed substitution of both chloro groups by methylamine yielded the title compound.
参考文献标题:Fluorescent 2,7-dialkylamino-[1,8]-naphthyridines: Preparation and spectroscopic properties
文献作者:Hoock,C.; et al.
参考来源:Molecules 1999,4264
合成路线:Hydroxynaphthyridinone (II),prepared from the amino derivative (I),was chlorinated to give dichloronaphthyridine (III).Subsequent copper-catalyzed substitution of both chloro groups by methylamine yielded the title compound.
参考文献标题:In vitro efficacy of 2,7-dialkylamino-[1,8]-naphtyridines against influenza viruses A and B
文献作者:Schmidtke,M.; et al.
参考来源:13th Intl Conf Antiviral Res 2000,84