新产品编号:350131
Chemical Name: 1-(6-Amino-1,3-benzodioxol-5-yl)-3-(3-methoxyphenyl)-2(E)-propen-1-one
CAS No. 204841-35-0
项目整合开发状态: Biological Testing
项目研究机构: University of North Carolina (Originator)
合成路线:The compound was prepared by condensation of acetophenone (I) with 3-flourobenzaldehyde (II) in refluxing ethanolic NaOH,followed by cyclization of the intermediate chalcone in diphenyl ether at 180 C.
合成路线:The desired 2'-amino chalcone is synthesized by a base-catalyzed condensation of 2-amino acetophenone (I) and benzaldehyde (II) by means of aqueous NaOH in EtOH.
📌 参考资料/链接：
参考文献标题:Antitumor agents.181.Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents
文献作者:Xia,Y.; Yang,Z.Y..; Xia,P.; Bastow,K.F.; Tachibana,Y.; Kuo,S.C.; Hamel,E.; Hackl,T.; Lee,K.H.
参考来源:J Med Chem 1998,41(7),1155
📄 详细内容
合成路线:The desired 2'-amino chalcone is synthesized by a base-catalyzed condensation of 2-amino acetophenone (I) and benzaldehyde (II) by means of aqueous NaOH in EtOH.
参考文献标题:Antitumor agents.Part 202: Novel 2'-amino chalcones: Design,synthesis and biological evaluation
文献作者:Xia,Y.; Yang,Z.Y.; Xia,P.; Bastow,K.F.; Nakanishi,Y.; Lee,K.H.
参考来源:Bioorg Med Chem Lett 2000,10(8),699
产品链接: CAS No. 204841-35-0››