AWD-33-159
Chemical Name: 4-Amino-1-(2-chlorophenyl)pyridin-2(1H)-one
CAS No. 256653-53-9
项目整合开发状态: Preclinical
项目研究机构: AWD.pharma (Originator)
合成路线:The title N-phenylpyrimidinone was prepared from the previously reported pyrimidine cyano ester (I) by alkaline hydrolysis with 10% NaOH followed by heating at 180 C in 75% H2SO4..
📌 参考资料/链接：
参考文献标题:New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and method for producing same
文献作者:Bartsch,R.; Rostock,A.; Lankau,H.-J.; Unverferth,K.; Arnold,T.; Granik,V.; Grizik,S.(AWD.pharma GmbH & Co.KG)
参考来源:DE 19835918; EP 1102748; JP 2002522420; WO 0007988